|Millennium:||1st millennium BC|
|454 BC by topic|
|Gregorian calendar||454 BC|
|Ab urbe condita||300|
|Ancient Egypt era||XXVII dynasty, 72|
|- Pharaoh||Artaxerxes I of Persia, 12|
|Ancient Greek era||81st Olympiad, year 3|
|Balinese saka calendar||N/A|
|Chinese calendar||丙戌年 (Fire Dog)|
2244 or 2037
— to —
丁亥年 (Fire Pig)
2245 or 2038
|Coptic calendar||−737 – −736|
|Ethiopian calendar||−461 – −460|
|- Vikram Samvat||−397 – −396|
|- Shaka Samvat||N/A|
|- Kali Yuga||2647–2648|
|Iranian calendar||1075 BP – 1074 BP|
|Islamic calendar||1108 BH – 1107 BH|
|Minguo calendar||2365 before ROC|
|Thai solar calendar||89–90|
−327 or −708 or −1480
— to —
−326 or −707 or −1479
Year 454 BC was a year of the pre-Julian Roman calendar. At the time, it was known as the Year of the Consulship of Capitolinus and Varus (or, less frequently, year 300 Ab urbe condita). The denomination 454 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
- Persian rule in Egypt is finally restored by Megabyzus, satrap of Syria, after a prolonged struggle which has included dealing with a military intervention by Athens. The leader of the revolt, Inaros, is crucified by the Persians.
- Mahavira attains Kevala Jnana at the age of 43, according to the Sweetámbara branch of Jain philosophy.
- Pericles leads a naval expedition in the Corinthian Gulf, in which Athens defeats Achaea. He then attacks Sicyon and Acarnania, after which he unsuccessfully tries to take Oeniadea on the Corinthian Gulf, before returning to Athens.
- Pericles declares that the Delian League's considerable treasury at Delos is not safe from the Persian navy and has the treasury transferred to Athens, thus strengthening Athens' power over the League.
- The Roman Plebs, suffering from a number of economic and financial ills, force the city’s patricians to begin the reform and codification of the law. As a first act, a three-man commission is sent to Athens to study that city's laws.
- Hostilities between Segesta and Selinunte, two Greek cities on Sicily, take place over access to the Tyrrhenian Sea.